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National Institutes of Health defines cloning

http://stemcells.nih.gov/info/glossary.asp

Clone— (v) To generate identical copies of a region of a DNA molecule or to generate genetically identical copies of a cell, or organism; (n) The identical molecule, cell, or organism that results from the cloning process.

  • In reference to DNA: To clone a gene, one finds the region where the gene resides on the DNA and copies that section of the DNA using laboratory techniques.
  • In reference to cells grown in a tissue culture dish: a clone is a line of cells that is genetically identical to the originating cell. This cloned line is produced by cell division (mitosis) of the original cell.
  • In reference or organisms: Many natural clones are produced by plants and (mostly invertebrate) animals. The term clone may also be used to refer to an animal produced by somatic cell nuclear transfer (SCNT) or parthenogenesis.

Somatic cell nuclear transfer (SCNT)—A technique that combines an enucleated egg and the nucleus of a somatic cell to make an embryo. SCNT can be used for therapeutic or reproductive purposes, but the initial stage that combines an enucleated egg and a somatic cell nucleus is the same. See also therapeutic cloning and reproductive cloning.

Enucleated—Having had its nucleus removed.

Somatic cell—Any body cell other than gametes (egg or sperm); sometimes referred to as "adult" cells. See also Gamete.

Gamete—An egg (in the female) or sperm (in the male) cell. See also Somatic cell.

Therapeutic cloning—The process of using somatic cell nuclear transfer (SCNT) to produce cells that exactly match a patient. By combining a patient's somatic cell nucleus and an enucleated egg, a scientist may harvest embryonic stem cells from the resulting embryo that can be used to generate tissues that match a patient's body. This means the tissues created are unlikely to be rejected by the patient's immune system. See also Somatic cell nuclear transfer (SCNT).

Reproductive cloning—The process of using somatic cell nuclear transfer (SCNT) to produce a normal, full grown organism (e.g., animal) genetically identical to the organism (animal) that donated the somatic cell nucleus. In mammals, this would require implanting the resulting embryo in a uterus where it would undergo normal development to become a live independent being. The first animal to be created by reproductive cloning was Dolly the sheep, born at the Roslin Institute in Scotland in 1996. See also Somatic cell nuclear transfer (SCNT).

 
 
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